布莱德湖阿珀姆

布莱德湖阿珀姆
  • 副教授,儿科和人类发展部
  • 食品安全
  • 1129农场LN 243室
  • 东兰辛密歇根48824
  • 517-884-2051

研究兴趣

Dr. Upham works in the area of genetic toxicology and oncology. Current research projects involve determining the cellular mechanisms by which nutrition, oxidative stress, and environmental & food borne contaminants affect cell proliferative, differentiation and apoptotic processes that ultimately cumulates into states of human diseases such as cancer. Studies on cellular mechanisms focus primarily on how intracellular signal transduction pathways and gap junctional intercellular communication collaboratively orchestrate the epigenetic expression of genes in rodent and human stem cell model systems. These mechanistic based results are important in identifying molecular targets for chemoprevention, -intervention and -therapeutic strategies for the control of human diseases such as cancer. These results are also important in determining a more accurate assessment of risk of these chemicals on human health. He also use various in vitro bioassays of cell communication to estimate the risk of epigenetic toxicity of environmental toxicants in the design of engineered environmental remediation systems.


学历

新罕布什尔大学, 理学士1981年,生物  
新罕布什尔大学, 多发性硬化症。,1983年,植物学   
密JDB电子游戏, 多发性硬化症。,1993年,环境JDB电子游戏及工程 
Virginia Polytech. & S. U, 博士,1986年,工厂physiol./biochem

下属网站

//phd.msu.edu/research/faculty-staff/brad-l-upham


出版物

博士。阿珀姆在考研

博士。阿珀姆在密JDB电子游戏的学者